$adrenal cortex fractions$

Therefore, the authors concluded that radiotherapy may play an important role in the care of patients with ACC. In those with advanced disease, a response to radiotherapy was observed in 57% of patients who received palliative radiotherapy. In an adjuvant setting, postoperative radiotherapy was able to prevent local recurrence in the majority of patients. Furthermore, patterns of failure after adjuvant radiotherapy were investigated, and the authors provided recommendations for patient selection, treatment planning, and treatment protocols. In addition, 26 patients were identified in the German ACC Registry who received palliative radiotherapy.

$adrenal cortex fractions$

Ten articles were identified that covered radiotherapy in a total of 129 patients with ACC (64 patients received postoperative irradiation, and 65 patients received palliative therapy for advanced disease). Original articles and reviews were identified using a PubMed search strategy that included the period up to July 2008.

$adrenal cortex fractions$

Because the role of radiotherapy is not defined well and because ACC often is considered radioresistant, the authors reviewed the available data on radiotherapy for ACC. Systemic treatment options still have limited efficacy. Even after radical surgery, up to 85% of patients develop recurrent disease. Adrenocortical carcinoma (ACC) is a rare malignancy, and patients with ACC have a poor prognosis.

$adrenal cortex fractions$

Adrenal cortex fractions